|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Inherited DNA-Repair Defects in Colorectal Cancer.
|
29478780 |
2018 |
|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
|
27978560 |
2017 |
|
| Entrez Id: |
472 |
| Gene Symbol: |
ATM |
ATM
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades.
|
28093285 |
2017 |
|
| Entrez Id: |
472 |
| Gene Symbol: |
ATM |
ATM
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
|
28135145 |
2017 |
|
| Entrez Id: |
472 |
| Gene Symbol: |
ATM |
ATM
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
|
27978560 |
2017 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.
|
28135145 |
2017 |
|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
A pathology atlas of the human cancer transcriptome.
|
28818916 |
2017 |
|
| Entrez Id: |
6224 |
| Gene Symbol: |
RPS20 |
RPS20
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.
|
27713038 |
2017 |
|
| Entrez Id: |
5795 |
| Gene Symbol: |
PTPRJ |
PTPRJ
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Tumor Suppressor PTPRJ Is a Target of miR-155 in Colorectal Cancer.
|
28316102 |
2017 |
|
| Entrez Id: |
4436 |
| Gene Symbol: |
MSH2 |
MSH2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.900 |
Biomarker |
CLINGEN |
Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer.
|
27329137 |
2016 |
|
| Entrez Id: |
64218 |
| Gene Symbol: |
SEMA4A |
SEMA4A
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.
|
27476653 |
2016 |
|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
|
| Entrez Id: |
4437 |
| Gene Symbol: |
MSH3 |
MSH3
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis.
|
27476653 |
2016 |
|
| Entrez Id: |
580 |
| Gene Symbol: |
BARD1 |
BARD1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer.
|
27197561 |
2016 |
|
| Entrez Id: |
11200 |
| Gene Symbol: |
CHEK2 |
CHEK2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Homozygous inactivation of CHEK2 is linked to a familial case of multiple primary lung cancer with accompanying cancers in other organs.
|
27900359 |
2016 |
|
| Entrez Id: |
999 |
| Gene Symbol: |
CDH1 |
CDH1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis.
|
26742007 |
2016 |
|
| Entrez Id: |
6597 |
| Gene Symbol: |
SMARCA4 |
SMARCA4
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A.
|
27852072 |
2016 |
|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer.
|
27329137 |
2016 |
|
| Entrez Id: |
22909 |
| Gene Symbol: |
FAN1 |
FAN1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability.
|
26797144 |
2016 |
|
| Entrez Id: |
5395 |
| Gene Symbol: |
PMS2 |
PMS2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.640 |
Biomarker |
CLINGEN |
Lynch syndrome caused by germline PMS2 mutations: delineating the cancer risk.
|
25512458 |
2015 |
|
| Entrez Id: |
2052 |
| Gene Symbol: |
EPHX1 |
EPHX1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
22909 |
| Gene Symbol: |
FAN1 |
FAN1
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Germline Mutations in FAN1 Cause Hereditary Colorectal Cancer by Impairing DNA Repair.
|
26052075 |
2015 |
|
| Entrez Id: |
64332 |
| Gene Symbol: |
NFKBIZ |
NFKBIZ
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
6597 |
| Gene Symbol: |
SMARCA4 |
SMARCA4
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.
|
25058500 |
2015 |
|
| Entrez Id: |
79728 |
| Gene Symbol: |
PALB2 |
PALB2
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
0.300 |
Biomarker |
CLINGEN |
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.
|
25980754 |
2015 |